Disease ecology of bats--the Canadian scene

Bats are hosts to a range of pathogens, which include zoonotic pathogens and pathogens of conservation concern. Brock Fenton's research on bat ecology has always balanced clear communication of potential health risks associated with bats and the need to communicate these risks precisely to avoid unnecessary persecution of bats. Here, we integrate Brock's work in the field of disease ecology with that of his students and collaborators and consider the potential advantages of studying disease ecology of bats within the Canadian context. The broad distribution of a few common species across the vast landscape of present-day Canada provides an opportunity to untangle the impacts of environmental variation on host-pathogen interactions and disease severity, particularly in the context of climate change. The varying migratory strategies and social structure of the bat species found in Canada could also facilitate informative interspecific studies to better understand how bat health is affected by interactions among rapid environmental changes, physiological traits, and the social behaviour of different species. We propose a series of priority research questions and approaches that could further our understanding of bat health and disease ecology in Canada, inspired by the work of Brock, his colleagues, and students.

Why Zero Trust Framework Adoption has Emerged During and After Covid-19 Pandemic

The rise of COVID-19 brought an unprecedented change in the way people lived. It left several people in a work-from-home situation. This Paper aims to investigate the recent works which applied Zero Trust and the reason that this framework adoption has emerged during and after the Pandemic. In this regard, a questionnaire was prepared, and its results are reported. According to its results, with Zero Trust Architecture (ZTA) gaining skyrocket popularity and trust, for around 60% corporates, ZT Access is planned for future, while for around 30% corporates, the project is in pipeline. None of the organizations surveyed have the ZTA in place. 14% of organizations are uninterested in adopting ZTA. Plus, in past 2 years, the percentage of north American organizations having a ZTA on the plans to establish one in the next 12–18 months has shot up. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Predicting COVID-19 Related Corporate Bankruptcies Prior to the Pandemic

In a previous study, it was shown that firms approaching bankruptcy exhibited less chaos than pair match firms based on their SIC (standard industry classification) code that did not enter bankruptcy. Chaos can be used to compare systems as quantified by calculating the Lyapunov exponent. In this study, the exponent was calculated using time series of daily stock market returns. Given that unhealthy systems display less chaos than healthy systems, bankruptcy is considered in this study as an expression of an unhealthy system. The sudden emergence of the COVID-19 pandemic placed firms under stress. This study successfully uses the Lyapunov exponents calculated for pair match firms based on the newer NAICS (North American Industry Classification System) code prior to the emergence of the pandemic to predict bankruptcies occurring shortly afterwards.

Collecting data from a social network as a new method to explore recurrent corneal erosions syndrome

Purpose : Collecting medical data for clinical research studies needs tremendous perseverance. Yet, patients post a lot of their own personal health data on social media and share their experiences through international virtual support groups. Recurrent epithelial erosion (RCE) induces recurrent pain while reducing patients' quality of life. We report data of RCE patients who belong to an international English-speaking support group hosted by a social network. We aimed at better defining patients' symptomatology and the subjective efficacy of proposed treatments, and subsequently compared our results with literature. Methods : We designed a 24-question questionnaire consisting in three parts: demographics, clinical data and therapies. The treatments' efficacy to prevent RCE was scored through a semi-quantitative 4-gradescale (from 'no effect? to 'very efficient'). In May 2021, we posted a 6-month ephemeral hyperlink on the RCE support group forum (Facebook, Meta®) pointing at our questionnaire Results : The RCE group included 1856 members. We harvested 257 complete responses (13.8%;222 women and 35 men;average age =42+/-12 y). Responders were mostly North Americans (n=152;59.1%), and Caucasian (n=214;83.3%). Fewer than one-third of RCEs were attested by a corneal subspecialist MD (n=70;27.2%), whereas 91.8% were referred to a health care professional (n=236). The predominant symptom was acute awakening pain (n=198;77.0%). RCE significantly impaired patients' quality of life (n=176;68.4%). Daily wearing of an anti-Covid-19 surgical mask may have increased the frequency of episodes (n=41;16.0%). Among surgical procedures, manual debridement was the most performed (n=56;21.8%), effective in a third of patients (n=17;30.3%). PTK was performed in one-fifth of patients (n=52;20.2%), effective in two-thirds (n=31;59.6%). 176 patients (68.4%) were treated with hypertonic gel, which, according to the patients was the most efficient medical treatment d (n=103;58.5%;p<0.0001). Conclusions : To our knowledge, this is the first real-life study involving patients with RCE, and the second collecting data through a social network in ophthalmology. Our results are consistent with previous retrospective or prospective reports based on medical records despite responder selection bias. The use of social networks to collect real life data seems to be promisingly reliable as a medical evaluation tool.

American Empire and the "Indian Problem" in 2020: From COVID-19 Checkpoints to McGirt

As the Cheyenne River Sioux Tribe filed suit against the federal government for using coercive measures to disassemble their COVID-19 checkpoints, Indian Country at large celebrated a landmark legal win for tribal sovereignty. The first case study concerns the Cheyenne River Sioux Tribe's and the Oglala Sioux Tribe's establishment of highway checkpoints in response to the COVID-19 pandemic and the South Dakota government's attempt to infringe on these measures. The national borders of the United States demarcate the reaches of the nation as a settler colonial superpower and attest to the chaos of empire. [Extracted from the article] Copyright of American Quarterly is the property of Johns Hopkins University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

The effect of co-location on human communication networks

The ability to rewire ties in communication networks is vital for large-scale human cooperation and the spread of new ideas. We show that lack of researcher co-location during the COVID-19 lockdown caused the loss of more than 4,800 weak ties—ties between distant parts of the social system that enable the flow of novel information—over 18 months in the email network of a large North American university. Furthermore, we find that the reintroduction of partial co-location through a hybrid work mode led to a partial regeneration of weak ties. We quantify the effect of co-location in forming ties through a model based on physical proximity, which is able to reproduce all empirical observations. Results indicate that employees who are not co-located are less likely to form ties, weakening the spread of information in the workplace. Such findings could contribute to a better understanding of the spatiotemporal dynamics of human communication networks and help organizations that are moving towards the implementation of hybrid work policies to evaluate the minimum amount of in-person interaction necessary for a productive work environment. © 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.

North American COVID-19 Myocardial Infarction (NACMI) Risk Score for Prediction of In-Hospital Mortality.

Background: In-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is higher in those with COVID-19 than in those without COVID-19. The factors that predispose to this mortality rate and their relative contribution are poorly understood. This study developed a risk score inclusive of clinical variables to predict in-hospital mortality in patients with COVID-19 and STEMI. Methods: Baseline demographic, clinical, and procedural data from patients in the North American COVID-19 Myocardial Infarction registry were extracted. Univariable logistic regression was performed using candidate predictor variables, and multivariable logistic regression was performed using backward stepwise selection to identify independent predictors of in-hospital mortality. Independent predictors were assigned a weighted integer, with the sum of the integers yielding the total risk score for each patient. Results: In-hospital mortality occurred in 118 of 425 (28%) patients. Eight variables present at the time of STEMI diagnosis (respiratory rate of >35 breaths/min, cardiogenic shock, oxygen saturation of <93%, age of >55 â€‹years, infiltrates on chest x-ray, kidney disease, diabetes, and dyspnea) were assigned a weighted integer. In-hospital mortality increased exponentially with increasing integer risk score (Cochran-Armitage χ2, P â€‹< â€‹.001), and the model demonstrated good discriminative power (c-statistic â€‹= â€‹0.81) and calibration (Hosmer-Lemeshow, P â€‹= â€‹.40). The increasing risk score was strongly associated with in-hospital mortality (3.6%-60% mortality for low-risk and very high-risk score categories, respectively). Conclusions: The risk of in-hospital mortality in patients with COVID-19 and STEMI can be accurately predicted and discriminated using readily available clinical information.

Using gravity model to make store closing decisions: A data driven approach.

Many studies propose methods for finding the best location for new stores and facilities, but few studies address the store closing problem. As a result of the recent COVID-19 pandemic, many companies have been facing financial issues. In this situation, one of the most common solutions to prevent loss is to downsize by closing one or more chain stores. Such decisions are usually made based on single-store performance; therefore, the under-performing stores are subject to closures. This study first proposes a multiplicative variation of the well-known Huff gravity model and introduces a new attractiveness factor to the model. Then a forward-backward approach is used to train the model and predict customer response and revenue loss after the hypothetical closure of a particular store from a chain. In this research the department stores in New York City are studied using large-scale spatial, mobility, and spending datasets. The case study results suggest that the stores recommended being closed under the proposed model may not always match the single store performance, and emphasizes the fact that the performance of a chain is a result of interaction among the stores rather than a simple sum of their performance considered as isolated and independent units. The proposed approach provides managers and decision-makers with new insights into store closing decisions and will likely reduce revenue loss due to store closures.

Sex Differences in Clinical Characteristics, Management Strategies, and Outcomes of STEMI With COVID-19: NACMI Registry.

Background: Women with ST-segment elevation myocardial infarction (STEMI) had worse outcomes than men prior to the COVID-19 pandemic. Although concomitant COVID-19 infection increases mortality risk in STEMI patients, no studies have evaluated sex differences in this context. Methods: The North American COVID-19 STEMI registry is a prospective, multicenter registry of hospitalized STEMI patients with COVID-19 infection. We compared sex differences in clinical characteristics, presentation, management strategies, and in-hospital mortality. Results: Among 585 patients with STEMI and COVID-19 infection, 154 (26.3%) were women. Compared to men, women were significantly older, had a higher prevalence of diabetes and stroke/transient ischemic attack, and were more likely to be on statins on presentation. Men more frequently presented with chest pain, whereas women presented with dyspnea. Women more often had STEMI without an identified culprit lesion than men (33% vs 18%, P < .001). The use of percutaneous coronary intervention was significantly higher in men, whereas medical therapy was higher in women. In-hospital mortality was 33% for women and 27% for men (P = .22). Conclusions: In patients presenting with STEMI in the context of COVID-19, the in-hospital mortality rate was 30% and similar for men and women. Lack of an identifiable culprit lesion was common in the setting of COVID-19 for both sexes but more likely in women (1/3 of women vs 1/5 of men). Evaluation of specific underlying etiologies is underway to better define the full impact of COVID-19 on STEMI outcomes and better understand the observed sex differences.

Identifying essential critical infrastructure workers during the COVID-19 pandemic using standardized industry codes.

BACKGROUND: The Cybersecurity and Infrastructure Security Agency (CISA) produced an advisory list identifying essential critical infrastructure workers (ECIW) during the coronavirus disease 2019 (COVID-19) response. The CISA advisory list is the most common national definition of ECIW but has not been mapped to United States (U.S.) Census industry codes (CICs) to readily identify these worker populations in public health data sources. METHODS: We identified essential critical infrastructure industry designations corresponding to v4.0 of the CISA advisory list for all six-digit North American Industry Classification System (NAICS) codes and cross-walked NAICS codes to CICs. CICs were grouped as essential, non-essential, or mixed essential/non-essential according to component NAICS industries. We also obtained national estimated population sizes for NAICS and Census industries and cross-tabulated Census industry and occupation codes to identify industry-occupation pairs. RESULTS: We produced and made publicly available spreadsheets containing essential industry designations corresponding to v4.0 of the CISA advisory list for NAICS and Census industry titles and codes and population estimates by six-digit NAICS industry, Census industry, and Census industry-occupation pair. The CISA advisory list is highly inclusive and contains most industries and U.S. workers; 71.0% of Census industries comprising 80.6% of workers and 80.7% of NAICS industries comprising 87.1% of workers were designated as essential. CONCLUSIONS: We identified workers in essential critical infrastructure industries as defined by CISA using standardized industry codes. These classifications may support public health interventions and analyses related to the COVID-19 pandemic and future public health crises.

Comment

[...]in his year-end assessment of Brexit, Prime Minister Boris Johnson proudly highlighted a standards reversal as one of Brexit's signal achievements. Because the British government had rolled back its prohibition against using feet, inches, pints, and quarts, its centuries-old predecessor to the metric system, it was once again possible to produce Winston Churchill's beloved pint-sized bottle of whisky. The UKCA, some warned, might even provoke the kind of resistance that stalled the adoption of the metric system in Britain until its entry into the EU and led to a hybrid system of measurement in the United States. In other countries, especially the United States, where private industry seeking to make its investments more productive generated its own industrial standards using its traditional measurement system as a way of harnessing the forces of industrialization already underway, but also in the United Kingdom, and even in France where it originated, the metric system either was resisted or was rejected repeatedly. The acceptance of Transmission Control Protocol/Internet Protocol (TCP/IP) as a de facto standard for internetworking showed that the formal standards process could be an impediment to the next wave of industrialization, while circumventing the process offered advantages for governments and private investors alike.

Experience Report on the Use of Breakout Rooms in a Large Online Course

In this paper, we present our experience with the use of breakout rooms in a second year undergraduate Software Design course at a large North American institution. Following the switch to remote instruction during the coronavirus pandemic, we revamped our in-person Software Design course to be delivered as a flipped online course, making extensive use of in-lecture exercises completed during breakout rooms. We report on the structure and logistics of this lecture design (for a large class of 300+ students). To gain insights into the impact of the use of breakout rooms on student experience, we conducted weekly student surveys asking for feedback on the lectures and specifically on the use of breakout rooms. Although many students had positive feelings regarding the use of breakout rooms, a significant percentage of students (an average of 47% of the survey responses each week) expressed negative feelings toward them. In an end-of-term survey, we specifically asked students about what they felt worked best for breakout rooms in terms of group size and pre-assigned versus randomized groups, and if there were any other areas that they felt needed improvement. Some of the patterns we observed were that most students liked smaller groups (2-5 people), preferred staying in the same group throughout the semester, and enjoyed the use of breakout rooms as long as others in their room were active participants. We share the details of these survey results as well as the tips and lessons that we learned through this experience. © 2022 ACM.

Unveiling the Bioactive Potential of Fresh Fruit and Vegetable Waste in Human Health from a Consumer Perspective

Food supply disruption and shortage verified during the current pandemic events are a scenario that many anticipate for the near future. The impact of climate changes on food production, the continuous decrease in arable land, and the exponential growth of the human population are important drivers for this problem. In this context, adding value to food waste is an obvious strategy to mitigate food shortages, but there is a long way to go in this field. Globally, it is estimated that one-third of all food produced is lost. This is certainly due to many different factors, but the lack of awareness of the consumer about the nutritional value of certain foods parts, namely peels and seeds, is certainly among them. In this review, we will unveil the nutritional and bioactive value of the waste discarded from the most important fresh fruit and vegetables consumed worldwide as a strategy to decrease food waste. This will span the characterization of the bioactive composition of selected waste from fruits and vegetables, particularly their seeds and peels, and their possible uses, whether in our diet or recycled to other ends.

The Influence of Sentiments of Economic Agents on Pedestrians and Vehicle Crossings along the US–Mexico Border

This study aimed to investigate the impact of people’s sentiments toward border crossings on personal vehicle and pedestrian crossings along the US–Mexico border. This study focused on regional factors and employed data derived from Google Trends as a proxy for people’s sentiments. Monthly data from the first quarter of 2004 to February 2020 were used. Different regression models were used to address stationarity. After controlling for economic conditions and external events, the primary findings are as follows: first, pedestrian and personal vehicle crossings are sensitive to exchange rate fluctuations. Second, the economic cycle has a slightly higher impact on pedestrians than personal vehicle crossings. Third, an increase in the hostile environment toward immigration in the U.S. may negatively impact pedestrian crossings, especially in Texas. Moreover, a rolling regression was used to examine the impact of people’s sentiments on crossings over time.

The impact of differing audience sizes on referees and team performance from a North American perspective

The COVID-19 pandemic provides a natural experimental framework to comprehensively test the effect of crowds on both referees and players. We examine this from a North American perspective, using data from three major leagues: the National Basketball Association (NBA), National Football League (NFL) and National Hockey League (NHL). In all three leagues in the 2020–2021 season, matches were played either in empty stadiums or before diverse audience sizes. We find that the lockdown affects NBA and NFL results, by lowering the prospects of winning and the expected scoring points of the home team, when games are played without an audience. Conversely, the lockdown does not substantially influence the outcomes of NHL games. We also examine the effect of audience size on game outcomes using historical observations from the past decade, when no lockdown measures were in force. Interestingly, a larger audience size increases the chance of winning and the expected scoring points of the visiting team for NFL games. No significant effect of the audience size on match outcomes is observed for NBA or NHL games. Regarding referee decisions, spectators do not significantly influence referee calls of NHL matches. As for NBA and NFL, the lockdown significantly increases the total number of referee calls but does not prompt more biased decisions towards either of the teams. Finally, a larger audience leads to referee calls more favourable to the visiting team for NFL games. These results extend the literature regarding crowd pressure on the behaviour of players and officials, with an indication that the specific sports activity has a pivotal role in the response to a cheering audience.

The content and accessibility of spine surgery fellowship websites and the North American Spine Surgery (NASS) fellowship directory.

BACKGROUND CONTEXT: The North American Spine Society (NASS) spine fellowship directory is an established resource that provides applicants with access to important information about different fellowship programs. Additionally, some programs have created websites to provide information about their fellowship program. There has been limited research on the amount and breadth of information provided by these different resources. PURPOSE: To assess and compare the scope of information provided by the North American Spine Society (NASS) fellowship directory and individual fellowship program websites. STUDY DESIGN/SETTING: Web Content Accessibility Study. PATIENT SAMPLE: There were no patient data used in this study. All reported data were accessed from public websites and the NASS fellowship directory (August 2022 fellowships). OUTCOME MEASURES: Outcome measures were reported as the presence or lack thereof of 22 topics pertaining to the specifics of each individual spine fellowship program on both the NASS fellowship directory and individual fellowship program websites. METHODS: The NASS fellowship directory (August 2022 fellowships) and individual program websites were evaluated by two independent reviewers. Program websites were identified via Google search with a systematic protocol. Within each platform, the availability of various data were recorded. Twenty-four different data points were assessed for each program and were categorized into four main categories-general program information, fellow profiles, clinical roles, and nonclinical roles of the fellow. Chi-squared tests were used to compare differences in the availability of specific data provided by the NASS fellowship directory and individual program websites. RESULTS: Seventy-four fellowship programs were identified. The NASS fellowship directory was more likely to provide information about the application process, a description of the program, fellow salary, faculty members, case descriptions, and research requirements (p<.05). The program websites were more likely to provide information about current and previous fellows-including a list of current fellow(s), their education/training, and a list of the previous fellows and their job choice (p<.05). Program websites were also more likely to discuss rotation schedules, clinic expectations, research opportunities, journal club, institutional meetings, sponsored national meetings, and current/previous research (p<.05). However, certain information, including specific clinical responsibilities (eg, rotation schedule, call expectations, clinic expectations) and the profiles of current and previous fellows, were not well represented on either platform. CONCLUSIONS: There were significant differences in the type of information provided by the NASS fellowship directory and program websites. Furthermore, there were key pieces of information that were not well represented on either platform.

Fetal Surgery in the Era of SARS-CoV-2 Pandemic: A Single-Institution Review.

OBJECTIVE: To cope with the changing health care services in the era of SARS-CoV-2 pandemic. We share the institutional framework for the management of anomalous fetuses requiring fetal intervention at Mayo Clinic, Rochester, Minnesota. To assess the success of our program during this time, we compare intraoperative outcomes of fetal interventions performed during the pandemic with the previous year. PATIENTS: We implemented our testing protocol on patients undergoing fetal intervention at our institution between March 1, and May 15, 2020, and we compared it with same period a year before. A total of 17 pregnant patients with anomalous fetuses who met criteria for fetal intervention were included: 8 from 2019 and 9 from 2020. METHODS: Our testing protocol was designed based on our institutional perinatal guidelines, surgical requirements from the infection prevention and control (IPAC) committee, and input from our fetal surgery team, with focus on urgency of procedure and maternal SARS-CoV-2 screening status. We compared the indications, types of procedures, maternal age, gestational age at procedure, type of anesthesia used, and duration of procedure for cases performed at our institution between March 1, 2020, and May 15, 2020, and for the same period in 2019. RESULTS: There were no statistically significant differences among the number of cases, indications, types of procedures, maternal age, gestational age, types of anesthesia, and duration of procedures (P values were all >.05) between the pre-SARS-CoV-2 pandemic in 2019 and the SARS-CoV-2 pandemic in 2020. CONCLUSIONS: Adoption of new institutional protocols during SARS-CoV-2 pandemic, with appropriate screening and case selection, allows provision of necessary fetal intervention with maximal benefit to mother, fetus, and health care provider.